The ATS Foundation and the chILD Foundation have awarded Lawrence Nogee, MD, of Johns Hopkins University a grant for $80,000 to support his research in pediatric interstitial lung disease. Children’s interstitial lung disease (chILD) is the name for a group of illnesses that cause chronic breathing problems in children. In many children, the cause of their disease is unknown, which creates substantial barriers to treatment.
Dr. Nogee’s research will expand upon the results of an earlier study in which he found that three siblings with similar clinical symptoms each had a mutation in the CCR2 gene. In his current project, Dr. Nogee will try to amass further evidence that this mutation causes certain interstitial lung diseases. To do this, he will characterize how the CCR2 protein (coded by the CCR2 gene) behaves in people with this mutation. He will also test other children who have chILD to see if they have the genetic mutation. According to Dr. Nogee, “Collectively, these studies will establish whether CCR2 is the proximate cause of lung disease in these children and its potential role in chILD. Proving that a problem in this gene can cause lung problems will also be important information to researchers who are targeting this gene as a possible therapy for other diseases.”
Our portion of the grant funding was made possible through the fundraising efforts of the John Schwalm and the donors from the Crouch Girls FirstGiving Page. Their funds were designated for unknown familial lung disease and Dr. Nogee’s was selected from many applications by the ATS Foundation review board. We thank you for your efforts and look forward to the outcome of this promising research.